New approaches in medical imaging using plastic scintillating detectors
Creators
- 1. Univ. of Texas Southwestern Medical Center at Dallas, TX (United States)
- 2. Univ. of Texas at Dallas, TX (United States)
- 3. Brookhaven National Labs., Upton, NY (United States)
Description
A small animal imaging camera was built in our laboratory, using fast plastic scintillating detectors (τ = 2-4 ns) and position sensitive photomultipliers (Hamamatsu) digitized using flash ADCs. Pinhole collimators were used for 125I imaging to achieve submillimeter resolution with scintillating plates of 28 mm radius and 1.5 mm thickness. A high resolution PET module was constructed with arrays of 1.0 mm diameter plastic scintillating fibers. The feasibility of high resolution imaging was demonstrated by the study of brain blood flow in a rat using 125I IMP in single photon detection mode and with 64Cu PTSM by using PET mode. Construction of single photon and positron emission tomographic imaging systems for small animals and subsequently for human imaging is in progress. (orig.)
Additional details
Publishing Information
- Journal Title
- Nuclear Instruments and Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms
- Journal Volume
- 79
- Journal Issue
- 1-4
- Journal Page Range
- p. 921-925.
- ISSN
- 0168-583X
- CODEN
- NIMBEU
Conference
- Title
- 12. international conference on the application of accelerators in research and industry.
- Dates
- 2-5 Nov 1992.
- Place
- Denton, TX (United States).
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 25011132
- Subject category
- S46: INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ALBUMINS; ANALOG-TO-DIGITAL CONVERTERS; BLOOD FLOW; BRAIN; COLLIMATORS; COPPER 64; DATA ACQUISITION SYSTEMS; FIBER OPTICS; GAMMA CAMERAS; GAMMA DETECTION; IODINE 125; MICE; NEOPLASMS; PLASTIC SCINTILLATION DETECTORS; POSITION SENSITIVE DETECTORS; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; SPATIAL RESOLUTION
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CAMERAS; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; COPPER ISOTOPES; DAYS LIVING RADIOISOTOPES; DETECTION; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; ELECTRONIC EQUIPMENT; EMISSION COMPUTED TOMOGRAPHY; EQUIPMENT; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IODINE ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; MEASURING INSTRUMENTS; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; OPTICS; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIATION DETECTION; RADIATION DETECTORS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RESOLUTION; RODENTS; SCINTILLATION COUNTERS; SOLID SCINTILLATION DETECTORS; TOMOGRAPHY; VERTEBRATES