Prognostic factors of myocardial perfusion imaging in patients with acute myocardial infarction having nonviable myocardium

The purpose of this study is to evaluate prognostic factors of myocardial perfusion imaging (MPI) in patients with acute myocardial infarction (AMI) showing nonviable myocardium on MPI. Subjects were 30 patients (M:F=26:4) of AMI treated medically. They underwent MPI within 1 month of AMI attack using Tc-99m-tetrofosmin and adenosine. They were followed for 30.6+15.7 months. Four cardiac events were developed including 2 cardiac death and 2 recurrent MI. Univariate analysis showed uptake of infarct area (P=0.03) and size of necrotic area (P=0.05) as significant prognostic factors. Multivariate analysis showed that uptake of infarct area was the only significant factor. In conclusion, lower uptake in nonviable myocardium is related to poor prognosis in AMI patients. (authors)