Published July 1974 | Version v1
Journal article Metadata-only

A precise evaluation of glomerular filtration rate (GFR) in two plasma samples following a single administration of 57Co-B12 vitamin

Creators

  • 1. Sao Paulo Univ. (Brazil). Faculdade de Medicina

Description

Through a logarithmic regression performed with the contings of 4 plasma samples withdrawn at 20,40,60 and 80 minutes after a venous injection of vitamin B12-57Co, the glomerular filtration-rate(GFR) in 11 patients, performing simultaneously the same study with EDTA-51Cr in 3 of them, is evaluated. The values obtained through the regression straight line are compared with those given by only 2 points, in the 6 possible combinations: 20 and 40 minutes, 20 and 60 minutes, 20 and 80 minutes, 40 and 60 minutes, 40 and 80 minutes, 60 and 80 minutes. The pair of points obtained at 20 and 80 minutes determined the straight line most similar to the logarithmic regression and as a simplification of the method, the withdraw of only 2 plasma samples, at and 80 minutes after a single injection of vitamin B12-57Co is proposed

Abstract (Portuguese)

Atraves de regressao lagaritmica efetuada com as leituras das atividades de quatro amostras de plasma retiradas aos 20,40,60 e 80 minutos apos injecao venosa de vitamina B12-57Co, avalia-se a filtracao glomerular (FG) em 11 individuos, fazendo simultaneiamente o mesmo estudo com EDTA-51Cr em tres deles. A seguir comparam os valores obtidos atraves da reta de regressao com aqueles conseguidos utilizando apenas dois pontos, nas seis combinacoes possiveis: 20 e 40 munutos, 20 e 60 minutos, 20 e 80 minutos, 40 e 60 minutos, 40 e 80 minutos, 60 e 80 minutos. Verifica-se que o par de pontos obtidos aos 20 e 60 minutos determina a reta que mais se aproxima da regressao logaritmica. Propoe-se como simplificacao do metodo, a retirada de apenas duas amostras de plasma, aos 20 e aos 80 minutos apos injecao unica de vitamina B12-57Co

Additional details

Additional titles

Original title (Portuguese)
Avaliacao precisa da filtracao glomerular (FG) com duas amostras de plasma apos injecao unica de vitamina B

Publishing Information

Journal Title
Rev. Hosp. Clin., Fac. Med., Univ. Sao Paulo
Journal Volume
29
Journal Issue
4
Series
Rev. Hosp. Clin., Fac. Med., Univ. Sao Paulo.
Journal Page Range
189-194

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
9417771
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
CHROMIUM 51; COBALT 57; DIAGRAMS; EDTA; GLOMERULI; RADIOPHARMACEUTICALS; RENAL CLEARANCE; VITAMIN B-12
Descriptors DEC
AMINO ACIDS; BETA DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CHELATING AGENTS; CHROMIUM ISOTOPES; CLEARANCE; COBALT ISOTOPES; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; EXCRETION; INFORMATION; INTERMEDIATE MASS NUCLEI; ISOTOPES; KIDNEYS; LABELLED COMPOUNDS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; VITAMIN B GROUP; VITAMINS