Published May 2021 | Version v1
Journal article Metadata-only

[99mTc]Tc-iPSMA SPECT brain imaging as a potential specific diagnosis of metastatic brain tumors and high-grade gliomas

Creators

  • 1. Departament of Nuclear Medicine, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, IMSS, Mexico City 06720 (Mexico)
  • 2. Department of Pathology, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, IMSS, Mexico City 06720 (Mexico)
  • 3. Department of Neurosurgery, Hospital de Especialidades del Centro Médico Nacional Siglo XXI, IMSS, Mexico City 06720 (Mexico)
  • 4. Department of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, 52750, Mexico State (Mexico)

Description

PSMA (prostate-specific membrane antigen) protein is heavily expressed in the proliferating microvasculature of high-grade gliomas (HGG) and brain metastases (BM). This research aimed to assess [99mTc]Tc-iPSMA SPECT brain imaging as a potential specific diagnosis of HGG and BM by PSMA-targeting in their proliferating vasculature.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.nucmedbio.2021.02.003

Additional details

Identifiers

DOI
10.1016/j.nucmedbio.2021.02.003;
PII
S0969805121000305;

Publishing Information

Journal Title
Nuclear Medicine and Biology
Journal Volume
96
Journal Page Range
p. 1-8
ISSN
0969-8051
CODEN
NMBIEO

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
53120618
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANTIGENS; BRAIN; DIAGNOSIS; GLIOMAS; METASTASES; PROSTATE; PROTEINS; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TECHNETIUM 99
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MALE GENITALS; NEOPLASMS; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; TECHNETIUM ISOTOPES; TOMOGRAPHY; YEARS LIVING RADIOISOTOPES

Optional Information

Copyright
Copyright (c) 2021 Elsevier Inc. All rights reserved.