Published 1983
| Version v1
Book
Interactions between nucleic acids and antibodies to Z-DNA
- 1. Centre National de la Recherche Scientifique, Orleans, France
Description
In this paper we report some properties of the antibodies to Z-DNA. To determine more precisely the antigenic determinant, the interactions between the antibodies and several polynucleotides have been studied. We found that the antibodies bind very weakly to poly(dI-br5dC).(dI-br5dC). This polynucleotide can adopt the Z conformation in high salt concentration, as we have demonstrated by infrared spectroscopy. Moreover, from the study of the exchange rate of the protons involved in hydrogen bonds in this polynucleotide and from previous studies on poly(dG-dC).poly(dG-dC) (Ramstein and Leng 1980; Pilet and Leng 1982), we propose a quantitative description of the dynamic structure of the Z form. 34 references, 5 figures, 3 tables
Additional details
Publishing Information
- Publisher
- Cold Spring Harbor Laboratory.
- Imprint Place
- Cold Spring Harbor, NY (USA)
- Imprint Title
- Cold Spring Harbor symposia on quantitative biology. Volume XLVII, Part 1. Structures of DNA
- Journal Page Range
- p. 163-170.
Conference
- Title
- 47. Cold Spring Harbor symposium - quantitative biology.
- Dates
- 2-9 Jun 1982.
- Place
- Cold Spring Harbor, NY (USA).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 16077606
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ANTIBODIES; DNA; DROSOPHILA; MOLECULAR STRUCTURE; RADIOIMMUNOASSAY; RECEPTORS; TRITIUM
- Descriptors DEC
- ANIMALS; ARTHROPODS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; FLIES; FRUIT FLIES; HYDROGEN ISOTOPES; INSECTS; INVERTEBRATES; ISOTOPE APPLICATIONS; ISOTOPES; LIGHT NUCLEI; NUCLEI; NUCLEIC ACIDS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; TRACER TECHNIQUES; YEARS LIVING RADIOISOTOPES