Published August 1, 2019 | Version v1
Journal article

Initial performance evaluation of a 3D gel dosimeter based on modified tetrazolium compounds

  • 1. London Regional Cancer Program, London Health Sciences Centre, London, ON, N6A 4L6 (Canada)
  • 2. Modus Medical Devices Inc., 1570 N Routledge Park, London, ON, N6H 5L6 (Canada)
  • 3. Department of Chemical and Biochemical Engineering, The University of Western Ontario, London, ON, N5A 5B9 (Canada)

Description

Tetrazolium-based 3D gellan gum gel dosimeters have been reported previously and tested at several sites. They show no image diffusion and excellent stability; however, the dose sensitivity of the current commercial product, ClearView™, is relatively low for routine clinical applications. Here we report initial testing of a second generation product with increased sensitivity and retained non-diffusive properties. This formulation has a 25% increase in sensitivity relative to ClearView™. However, the sample has a higher initial attenuation and the background attenuation increases faster than ClearView™. The composition was tested in a 1-liter sealed container using a 2x2 cm, 6MV, x-ray beam, and show agreement between Monte Carlo simulation and measurements. (paper)

Availability note (English)

Available from http://dx.doi.org/10.1088/1742-6596/1305/1/012036

Additional details

Publishing Information

Journal Title
Journal of Physics. Conference Series (Online)
Journal Volume
1305
Journal Issue
1
Journal Page Range
[4 p.]
ISSN
1742-6596

Conference

Title
10. International Conference on 3D Radiation Dosimetry
Acronym
IC3DDose
Dates
16-19 Sep 2018
Place
Kunshan (China)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
53045452
Subject category
S61: RADIATION PROTECTION AND DOSIMETRY; S36: MATERIALS SCIENCE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ATTENUATION; COMPUTERIZED SIMULATION; DOSEMETERS; GELS; MONTE CARLO METHOD; PERFORMANCE; RADIATION DOSES; SENSITIVITY; TESTING; THREE-DIMENSIONAL CALCULATIONS; X RADIATION
Descriptors DEC
CALCULATION METHODS; COLLOIDS; DISPERSIONS; DOSES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MEASURING INSTRUMENTS; RADIATIONS; SIMULATION