Published 2005 | Version v1
Miscellaneous Metadata-only

Nanoporosity in a self-assembled drug delivery system detected by positron annihilation lifetime spectroscopy

Creators

  • 1. University of Muenster (Germany). Institute of Physical Chemistry
  • 2. Commonwealth Scientific and Research Organisation, Clayton, VIC (Australia). Manufacturing and Infrastructure Technology
  • 3. Monash University, VIC (Australia). School of Chemistry

Description

Full text: We present a new drug carrier system that consists of silica hybrid gels having organic side groups. A major difference to existing formulations is that the matrix is generated in the presence of the drug molecule in a self-assembling process. The critical role of pore architecture (size and accessibility) in the tailored drug release is clearly revealed by positron annihilation lifetime spectroscopy (PALS), while the classical nitrogen adsorption technique (BET method) is not suitable here to indicate the internal void structure. Copyright (2005) Australian Institute of Physics

Part of:
16th National Congress of the Australian Institute of Physics. Congress Proceedings Handbook and Abstracts

Additional details

Identifiers

URL
http://aipcongress2005.anu.edu.au/pdf/AIPC_Handbook_V2.pdf;

Publishing Information

Imprint Title
16th National Congress of the Australian Institute of Physics. Congress Proceedings Handbook and Abstracts
Imprint Pagination
268 p.
Journal Page Range
p. 161

Conference

Title
16. National Congress of the Australian Institute of Physics. Physics for the Nation
Dates
30 Jan - 4 Feb 2005
Place
Canberra, ACT (Australia)

INIS

Country of Publication
Australia
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37101689
Subject category
S75: CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY;
Resource subtype / Literary indicator
Conference, Non-conventional Literature
Descriptors DEI
ADSORPTION; ANNIHILATION; DELIVERY; DRUGS; GELS; LIFETIME; MOLECULES; NANOSTRUCTURES; NITROGEN; POSITRONS; SILICA; SPECTROSCOPY
Descriptors DEC
ANTILEPTONS; ANTIMATTER; ANTIPARTICLES; COLLOIDS; DISPERSIONS; ELEMENTARY PARTICLES; ELEMENTS; FERMIONS; INTERACTIONS; LEPTONS; MATTER; MINERALS; NONMETALS; OXIDE MINERALS; PARTICLE INTERACTIONS; SORPTION

Optional Information