Published March 2021 | Version v1
Journal article

Long-Term Maintenance of Acinar Cells in Human Submandibular Glands After Radiation Therapy

  • 1. Department of Otolaryngology, University of Rochester School of Medicine and Dentistry, Rochester, New York (United States)
  • 2. Department of Pathology, University of Rochester School of Medicine and Dentistry, Rochester, New York (United States)
  • 3. Department of Radiation Oncology, University of Rochester School of Medicine and Dentistry, Rochester, New York (United States)
  • 4. Center for Oral Biology, Department of Biomedical Genetics, University of Rochester School of Medicine and Dentistry, Rochester, New York (United States)

Description

In a combined retrospective and prospective study, human salivary glands were investigated after radiation treatment for head and neck cancers. The aim was to assess acinar cell loss and morphologic changes after radiation therapy and to determine whether irradiated salivary glands have regenerative potential.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.ijrobp.2020.10.037

Additional details

Identifiers

DOI
10.1016/j.ijrobp.2020.10.037;
PII
S0360301620344837;

Publishing Information

Journal Title
International Journal of Radiation Oncology, Biology and Physics
Journal Volume
109
Journal Issue
4
Journal Page Range
p. 1028-1039
ISSN
0360-3016
CODEN
IOBPD3

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
53124553
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
HEAD; HUMANS; IRRADIATION; NECK; NEOPLASMS; RADIOTHERAPY; SALIVARY GLANDS
Descriptors DEC
ANIMALS; BODY; DISEASES; GLANDS; MAMMALS; MEDICINE; NUCLEAR MEDICINE; ORGANS; PRIMATES; RADIOLOGY; THERAPY; VERTEBRATES

Optional Information

Copyright
Copyright (c) 2020 Elsevier Inc. All rights reserved.