Published April 23, 2011 | Version v1
Journal article

Target and peripheral dose from radiation sector motions accompanying couch repositioning of patient coordinates with the Gamma Knife® Perfexion

  • 1. Department of Molecular and Cellular Biophysics and Biochemistry, Roswell Park Cancer Institute, Buffalo (United States)
  • 2. Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo (United States)
  • 3. Department of Physiology and Biophysics, State University of New York, Buffalo (United States)
  • 4. Department of Neurosurgery, Roswell Park Cancer Institute, Buffalo (United States)

Description

The GammaPlan treatment planning system (TPS) does not fully account for shutter dose when multiple shots are required to deliver a patient’s treatment. The unaccounted exposures to the target site and its periphery are measured in this study. The collected data are compared to a similar effect from the Gamma Knife® model 4C. A stereotactic head frame was attached to a Leksell® 16 cm diameter spherical phantom; using a fiducial-box, CT images of the phantom were acquired and registered in the TPS. Measurements give the relationship of measured dose to the number of repositions with the patient positioning system (PPS) and to the collimator size. An absorbed dose of 10 Gy to the 50% isodose line was prescribed to the target site and all measurements were acquired with an ionization chamber. Measured dose increases with frequency of repositioning and with collimator size. As the radiation sectors transition between the beam on and beam off states, the target receives more shutter dose than the periphery. Shutter doses of 3.53±0.04 and 1.59±0.04 cGy/reposition to the target site are observed for the 16 and 8 mm collimators, respectively. The target periphery receives additional dose that varies depending on its position relative to the target. The radiation sector motions for the Gamma Knife® Perfexion result in an additional dose due to the shutter effect. The magnitude of this exposure is comparable to that measured for the model 4C

Availability note (English)

Available from http://dx.doi.org/10.2478/v10019-011-0012-9; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423725

Additional details

Publishing Information

Journal Title
Radiology and Oncology
Journal Volume
45
Journal Issue
2
Journal Page Range
p. 132-142
ISSN
1318-2099

INIS

Country of Publication
Slovenia
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
46051498
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BEAMS; CAT SCANNING; COLLIMATORS; DOSIMETRY; HEAD; IMAGES; LIVER; PATIENTS; PHANTOMS; PLANNING; POSITIONING; SHUTTERS; SPHERICAL CONFIGURATION
Descriptors DEC
BODY; COMPUTERIZED TOMOGRAPHY; CONFIGURATION; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; GLANDS; MOCKUP; ORGANS; STRUCTURAL MODELS; TOMOGRAPHY

Optional Information

Copyright
Copyright (c) by Association of Radiology & Oncology
Notes
PMCID: PMC3423725; PMID: 22933947; PUBLISHER-ID: rado-45-02-132; OAI: oai:pubmedcentral.nih.gov:3423725; This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).