Routine simultaneous production of no-carrier-added high purity 64Cu and 67Ga
Creators
- 1. Atomic Energy Commission, Damascus (Syrian Arab Republic). Dept. of Chemistry
Description
A routine production method of no-carrier-added 64Cu was performed. A copper target support is electroplated by gold then an optimized thickness of enriched 68Zn layer is deposited. The 68Zn target was bombarded with 23.5 MeV and 250μA proton beam, generating the main nuclear reactions 68Zn(p,2n)67Ga and 68Zn(p,αn)64Cu. A semi-automated separation method using chromatographic columns system was developed for 64CuCl2 production. A 600 mCi batch of 64Cu is produced at the end of separation and purification chemistry. The Radionuclidic purity of 64Cu was >98% as required by US and European Pharmacopoeias. Radiochemical purity and activity concentration is suitable for labeling different ligands to produce diagnostic and therapeutic radiopharmaceuticals. (author)
Additional details
Publishing Information
- Journal Title
- Aalam Al-Zarra
- Journal Issue
- 139
- Journal Page Range
- p. 60
- ISSN
- 1607-985X
- CODEN
- AAALE5
INIS
- Country of Publication
- Syrian Arab Republic
- Country of Input or Organization
- Syrian Arab Republic
- INIS RN
- 43062961
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- COPPER 64; GALLIUM 67; ION EXCHANGE CHROMATOGRAPHY; ISOTOPE PRODUCTION; PROTON BEAMS; TARGETS; ZINC 68
- Descriptors DEC
- BEAMS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CHROMATOGRAPHY; COPPER ISOTOPES; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; GALLIUM ISOTOPES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; NUCLEI; NUCLEON BEAMS; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; PARTICLE BEAMS; RADIOISOTOPES; SEPARATION PROCESSES; STABLE ISOTOPES; ZINC ISOTOPES
Optional Information
- Notes
- Abstract of paper published in Nukleonika; 2011. v. 56(4) p. 259-26