Published July 2017
| Version v1
Journal article
Ultrasound-guided drug delivery in cancer
- 1. Dept. of Radiology, Stanford University School of Medicine, Stanford (United States)
Description
Recent advancements in ultrasound and microbubble (USMB) mediated drug delivery technology has shown that this approach can improve spatially confined delivery of drugs and genes to target tissues while reducing systemic dose and toxicity. The mechanism behind enhanced delivery of therapeutics is sonoporation, the formation of openings in the vasculature, induced by ultrasound-triggered oscillations and destruction of microbubbles. In this review, progress and challenges of USMB mediated drug delivery are summarized, with special focus on cancer therapy
Additional details
Publishing Information
- Journal Title
- Ultrasonography
- Journal Volume
- 36
- Journal Issue
- 3
- Series
- 96 refs, 6 figs, 1 tab
- Journal Page Range
- p. 171-184
- ISSN
- 2288-5919
INIS
- Country of Publication
- Korea, Republic of
- Country of Input or Organization
- Korea, Republic of
- INIS RN
- 48081828
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- DRUGS; GENES; NEOPLASMS; OSCILLATIONS; THERAPY; TOXICITY; ULTRASONOGRAPHY
- Descriptors DEC
- DIAGNOSTIC TECHNIQUES; DISEASES; MEDICINE