Published 1976 | Version v1
Report Metadata-only

Effect of foetal irradiation on hypothalamo-pituitary-adrenal system activity in adult rat

Creators

  • 1. Centre de Recherches du Service de Sante des Armees, 92 - Clamart (France). Div. de Radiobiologie Experimentale

Description

Pregnant females were exposed to a gamma irradiation of 150 rads on day 15 of gestation. The data obtained indicated that foetal irradiation reduced the weight of pituitary and adrenal glands. Nevertheless, the hypothalamo-pituitary-adrenal system of adult rat was not influenced by the foetal exposure. The normal endocrine activity of adult rat, in spite of the damage caused during foetal stage, seemed to be due to biological repair

Abstract (French)

Des femelles gravides ont ete exposees a une irradiation gamma de 150 rads au 15eme jour de la gestation. Les donnees obtenues ont montre que l'irradiation foetale a entraine une reduction du poids de l'hypophyse et des surrenales. Malgre cette atteinte, l'irradiation foetale n'a pas affecte l'activite de l'axe hypothalamo-hypophyso-surrenalien du rat adulte. L'activite endocrine normale de l'adulte, malgre les dommages causes au stade foetal, parait due a une restauration biologique

Additional details

Additional titles

Original title (French)
Effet de l'irradiation foetale sur l'activite de l'axe hypothalamo-hypophyso-surrenalien du rat devenu adulte

Publishing Information

Imprint Title
1976 scientific works
Journal Page Range
p. 52-54.
Report number
CRSSA-RA--1976

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
9414508
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Progress Report
Descriptors DEI
ADRENAL GLANDS; BIOLOGICAL FUNCTIONS; BIOLOGICAL RADIATION EFFECTS; FETUSES; GAMMA RADIATION; HYPOTHALAMUS; PITUITARY GLAND; PREGNANCY; RATS; WEIGHT
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; ELECTROMAGNETIC RADIATION; ENDOCRINE GLANDS; GLANDS; IONIZING RADIATIONS; MAMMALS; NERVOUS SYSTEM; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES

Optional Information

Notes
Imprint:Travaux scientifiques. Annee 1976.