Published July 1983
| Version v1
Journal article
Imitation of the effects of radiation on dna, and genetic hazards from radionuclide decay
Description
Dehydrogenation of DNA pyrimidine nucleotides in thymine positions 5 and 6 and cytosine position 5 is not a drastic lethal damage. Moreover, dehydrogenation of DNA in thymine positions 5 and 6 is not an effective mutagenic lesion. DNA dehydrogenation in cytosine position 5 has proved to be a pronounc dmutagenic damage. As to induction of point mutations, 3H is not more harmful than external γ-radiation given in equivalent doses
Additional details
Additional titles
- Subtitle (English)
- Dehydrogenation of pyrimidine nucleotides resulted from a decay of incorporated "3H
- Original title (Russian)
- Моделирование эффектов радиационных повреждений DNK и генетическая опасност' распада радионуклидов
- Original subtitle (Russian)
- Degidrirovanie pirimidinoVykh nukleotidov pri raspade inkorporirovannogo "3H.
Publishing Information
- Journal Title
- Radiobiologiya
- Journal Volume
- 23
- Journal Issue
- 4
- Series
- Radiobiologiya.
- Journal Page Range
- 458-461
- ISSN
- 0033-8192
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 15013272
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BETA PARTICLES; BIOLOGICAL MODELS; BIOLOGICAL RADIATION EFFECTS; CHEMICAL RADIATION EFFECTS; DEHYDROGENATION; DNA; DOSE-RESPONSE RELATIONSHIPS; GENOTYPE; LABELLED COMPOUNDS; MUTATION FREQUENCY; PYRIMIDINES; RADIOLYSIS; SACCHAROMYCES CEREVISIAE; TRITIUM COMPOUNDS
- Descriptors DEC
- AZINES; BIOLOGICAL EFFECTS; CHARGED PARTICLES; CHEMICAL REACTIONS; DECOMPOSITION; FUNGI; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PLANTS; RADIATION EFFECTS; SACCHAROMYCES; YEASTS
Optional Information
- Notes
- For English translation see the journal Radiobiology (Translation) (USA).