Published 1992
| Version v1
Miscellaneous
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Preparation of 99m Tc-methoxy isobutyl isonitrile
- 1. Office of Atomic Energy for Peace, Bangkok (Thailand)
Description
Preparation of 99mTc-methoxy isobutyl isonitrile (99mTc-MIBI), the myocardial imaging agent, has been studied. MIBI was synthesized from the condensation of 2-methylallylamine hydrochloride and ethylformate to obtain N-(2-methyl allyl) formamide followed by methoxylation and demercuration reactions to get methoxy isobutyl formamide then dehydrated the compound to obtain the product, MIBI. The lyophilized kit of MIBI was prepared and labelled with 99mTc. The radiochemical purity of the labelled kit was greater than 97%. Biodistribution in experimental animals is going to be studied
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Additional details
Publishing Information
- ISBN
- 974-7399-78-4
- Imprint Title
- The 4th Nuclear Science and Technology Conference. Proceedings
- Imprint Pagination
- 613 p.
- Journal Page Range
- p. 42-53.
- Report number
- INIS-mf--14323
Conference
- Title
- 4. Nuclear Science and Technology Conference.
- Dates
- 20-22 Oct 1992.
- Place
- Bangkok (Thailand).
INIS
- Country of Publication
- Thailand
- Country of Input or Organization
- Thailand
- INIS RN
- 26000183
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference, Numerical Data
- Descriptors DEI
- CHEMICAL PREPARATION; EXPERIMENTAL DATA; IMAGES; LABELLED COMPOUNDS; MYOCARDIAL INFARCTION; RADIOPHARMACEUTICALS; TECHNETIUM 99
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARDIOVASCULAR DISEASES; DATA; DISEASES; DRUGS; HOURS LIVING RADIOISOTOPES; INFORMATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATERIALS; NUCLEI; NUMERICAL DATA; ODD-EVEN NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; SYNTHESIS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES