Genetics of radiation sensitivity in the slime mould Dictyostelium discoideum

Mutations leading to increased sensitivity to 60Co gamma rays and/or ultraviolet light in the slime mould Dictyostelium discoideum have been assigned to eight loci on the basis of linkage and complementation tests. The linkages of these loci are: radA, linkage group I; radB, linkage group VI; radC, linkage group III; radD, linkage group IV; radF, linkage group IV; radG, linkage group III; radH, linkage group II; and radI, linkage group III. The radC mutants, which were isolated on the basis of increased sensitivity to ultraviolet light, are as resistant as their parental strains to 60Co gamma rays, whereas all other mutants studied are sensitive to both ultraviolet light and 60Co gamma rays. A new temperature-sensitive mutation, tsgL606, has been assigned to linkage group I. (author)