Late sequelae and complications in exclusive high voltage radiotherapy for carcinoma of the cervix uteri
- 1. Institut du Radium, 75 - Paris (France)
Description
524 cases of uterine cervix (except stade IV cases) completely treated at the foundation Curie with exclusive radiotherapy from 1962 to 1968 are studied. The irradiation techniques, as well as the doses given to the tumor and to the critical organs are stated. The various sequelae and complications are described, according to the class and severity. The rectal troubles are frequent (55% of all the troubles) in 40% of the patients; though rarely, they can be severe (6% of the cases). They appear relatively early. The bladder troubles rank second (37% of all the troubles) in 20% of the patients; never severe and without any renal effect, they are more delayed than the former. The skin and soft tissues troubles are only a few (5%) for 5% of the patients. They are mostly mild and moderate. One skin necrosis was noted due for a large part to the very poor general conditions of the patient. The bone troubles are always classified here as marked or severe; they are rare (2,6%) in 2,3% of the patients. Their treatment is satisfactory. One single case of bilateral femur neck fracture gave a permanent infirmity. The genital troubles noted in 21% of the patients are mostly vaginal adhesion in women over 60 years of age
Abstract (French)
524 cas de cancer du col uterin (stade IV excepte) entierement traites a la Fondation Curie, par radiotherapie exclusive, de 1962 a 1968 sont presentes. Les techniques d'irradiation ainsi que les doses administrees a la tumeur et aux organes critiques sont precisees. Les differentes sequelles et complications sont indiquees, classees par categorie et selon leur gravite. Les troubles rectaux sont frequents puisqu'ils representent 55% du total des troubles et surviennent chez 40% des malades; ils peuvent etre, quoique assez rarement, severes (chez 6% des malades). Leur apparition est relativement precoce. Les troubles vesicaux viennent en second lieu et constituent 37% du total des troubles, chez 20% des malades; jamais serieux et toujours sans retentissement renal, ils apparaissent plus tardivement que les precedents. Les troubles de la peau et des tissus mous sont peu nombreux, 5% du total des troubles, chez 5% des malades. Ce sont surtout des sequelles mineures et moderees. Une seule necrose cutanee, essentiellement due a un tres mauvais terrain, a ete relevee. Les complications osseuses, toujours considerees comme marquees ou majeures sont rares: 2,6% du total des troubles, chez 2,3% des malades. Leur traitement est efficace. Un seul cas de fracture bilaterale du col femoral a presente une importance definitive. Les sequelles genitales survenues chez 21% des malades, sont essentiellement constituees par des symphyses vaginales chez des malades qui ont plus de 60 ansAdditional details
Additional titles
- Original title (French)
- Les sequelles et complications tardives de la radiotherapie exclusive de haute energie des carcinomes du col uterin
Publishing Information
- Journal Title
- J. Radiol., Electrol., Med. Nucl.
- Journal Volume
- 57
- Journal Issue
- 5
- Series
- J. Radiol., Electrol., Med. Nucl.
- Journal Page Range
- 409-419
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 7270666
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CARCINOMAS; DELAYED RADIATION EFFECTS; RADIOTHERAPY; SIDE EFFECTS; UROGENITAL SYSTEM DISEASES
- Descriptors DEC
- BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; DISEASES; MEDICINE; NEOPLASMS; RADIATION EFFECTS; THERAPY