Published 1995
| Version v1
Journal article
Facile regio- and stereospecific 1,3-dipolar cycloaddition of metallo-azomethine ylides to ethyl (E)-4,4,4-trifluorobut-2-enoate
Creators
- 1. Centre d'Etudes Pharmaceutiques, 92 - Chatenay-Malabry (France)
Description
Ethyl (E)-4,4,4-trifluorobut-2-enoate undergoes regio-and stereospecific cycloaddition with metallo-azomethine ylides generated from the imines of glycine or alanine esters in the presence of silver acetate to give trifluoromethylpyrrolidines in excellent yields. This methodology has been applied to the synthesis of a range of substituted trifluoromethylpyrrolidines. (authors). 19 refs., 3 figs., 1 tab
Additional details
Publishing Information
- Journal Title
- Bulletin de la Societe Chimique de France
- Journal Volume
- 132
- Journal Issue
- 4
- Journal Page Range
- p. 402-405.
- ISSN
- 0037-8968
- CODEN
- BSCFAS
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 27021170
- Subject category
- S75: CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- ACETATES; ACRYLATES; ALANINES; ALKENES; COUPLING CONSTANTS; DECOUPLING; ESTERS; GLYCINE; IMINES; NUCLEAR MAGNETIC RESONANCE; PROLINE; STEREOCHEMISTRY; SYNTHESIS; TOLUENE; X-RAY DIFFRACTION
- Descriptors DEC
- ALKYLATED AROMATICS; AMINES; AMINO ACIDS; AROMATICS; AZOLES; CARBOXYLIC ACID SALTS; CARBOXYLIC ACIDS; COHERENT SCATTERING; DIFFRACTION; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HYDROCARBONS; MAGNETIC RESONANCE; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRROLES; PYRROLIDINES; RESONANCE; SCATTERING