Published 1991
| Version v1
Book
Induction of late expressed lethal mutations by radiation in synchronised CHO-KI cells as a function of cellular multiplicity and time post plating
Creators
- 1. Nuclear Energy Board, Dublin (Ireland)
- 2. Dublin Inst. of Technology (Ireland)
Description
The results presented clearly show that in synchronous populations of CHO-KI cells, no lethal mutations can be observed if the cells are irradiated at any time during the first cell cycle post plating. Increasing numbers of lethal mutations were seen during the second cell cycle. These results suggest that cell cycle phase at the time of irradiation is not involved in the mechanism leading to lethal mutation induction if only single cells are irradiated. (author)
Additional details
Publishing Information
- Publisher
- Taylor and Francis.
- Imprint Place
- London (United Kingdom)
- ISBN
- 0-7484-0020-6
- Imprint Title
- New developments in fundamental and applied radiobiology
- Imprint Pagination
- 460 p.
- Journal Page Range
- p. 132-137.
Conference
- Title
- 23. annual meeting of the European Society for Radiation Biology.
- Dates
- 23-26 Sep 1990.
- Place
- Dublin (Ireland).
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 23019011
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; CELL CYCLE; CHO CELLS; IN VITRO; LETHAL MUTATIONS; SYNCHRONOUS CULTURES; TIME DEPENDENCE
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL EFFECTS; CELL CULTURES; MUTATIONS; RADIATION EFFECTS; SOMATIC CELLS
Optional Information
- Contract/Grant/Project number
- Contract B17-0023-C