Published July 1993 | Version v1
Journal article

Accelerated heavy ions and the lens. Pt. 9

  • 1. Columbia Univ., New York, NY (United States). Eye Radiation and Environmental Research Lab.
  • 2. Lawrence Berkeley Lab., CA (United States). Life Sciences Div.

Description

Lenses of mice irradiated with 250 MeV protons, 670 MeV/amu 20Ne, 600 MeV/amu 56Fe, 350 MeV/amu 56Fe, 600 MeV/amu 93Nb or 593 MeV/amu 139La ions were evaluated by analysing cytopathological indicators which have been implicated in the cataractogenic process. The LETs ranged from 0.39 to 953 keV/μm and the fluences from 1.31 x 103/mm2 to 5.12 x 107/mm2. The lenses were assessed 64 weeks post-irradiation in order to observe the late effects of LET and dose on the target cell population of the lens' epithelium. Results showed that growth-dependent pathological changes occurred at the cellular level as a function of dose and LET. (author)

Additional details

Additional titles

Subtitle (English)
Late effects of LET and dose on cellular parameters in the murine lens

Publishing Information

Journal Title
International Journal of Radiation Biology
Journal Volume
64
Journal Issue
1
Journal Page Range
p. 103-111.
ISSN
0955-3002
CODEN
IJRBE7