Published May 1999
| Version v1
Journal article
Effect of ionizing radiation on apoptosis in the cortex of mouse lymph node
Creators
- 1. Norman Bethune Univ. of Medical Sciences, Dept. of Histology and Embryology (China)
- 2. MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences (China)
Description
Objective: To study the alteration of apoptosis in the cortex of mouse lymph node following whole body X-irradiation. Methods: The method of TdT-mediated dUTP nick end labelling (TUNEL) was used to detect apoptosis the cortex of mouse lymph node. Results: The sensitivity to high and low dose ionizing radiation was distinct in different area of the cortex. Conclusion: The decrease of apoptotic cells in the inter nodular and deep cortex indicate that low dose radiation may suppress the apoptosis of T lymphocytes and play a role in immune regulation
Additional details
Publishing Information
- Journal Title
- Journal of Norman Bethune University of Medical Sciences
- Journal Volume
- 25
- Journal Issue
- 3
- Journal Page Range
- p. 223-225
- ISSN
- 0253-3707
- CODEN
- PEIPDB
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 31041241
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CELL PROLIFERATION; IONIZING RADIATIONS; LOW DOSE IRRADIATION; LYMPH NODES; LYMPHOCYTES; MICE; SENSITIVITY; WHOLE-BODY IRRADIATION; X RADIATION
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; IONIZING RADIATIONS; IRRADIATION; LEUKOCYTES; LYMPHATIC SYSTEM; MAMMALS; MATERIALS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES