Published November 2005 | Version v1
Journal article Metadata-only

Diploflavone, a New Flavonoid from Diplotropis ferruginea Benth. (Fabaceae)

Creators

  • 1. Universidade Federal do Vale do Sao Francisco, Petrolina, PE (Brazil)
  • 2. Universidade Federal da Paraiba, Joao Pessoa, PB (Brazil). Lab. de Tecnologia Farmaceutica
  • 3. Universidade Estadual da Paraiba, Campina Grande, PB (Brazil). Dept. de Farmacia
  • 4. Universidade Federal de Pernambuco, Recife, PE (Brazil). Dept. de Antibioticos
  • 5. Universidade Estadual do Norte Fluminense (UENF), Campos dos Goytacases, RJ (Brazil). Setor de Quimica de Produtos Naturais. Lab. de Ciencias Quimicas

Description

The chemical examination of Diplotropis ferruginea Benth. resulted in the isolation of a new 3-methoxyflavone, 3-methoxy-6-O-prenyl-6,6-dimethylchromene-(7,8,2,3)-flavone, to which was given the trivial name diploflavone (1); as well as the known 3,6-dimethoxy-6,6- dimethylchromene-(7,8,2,3)-flavone (2). The structure of the new compound was established by spectral analyses. Cytotoxic activity of the isolated compounds was tested against the cells NClH292 (lung carcinoma), HEp-2 (larynx carcinoma) and KB (oral epidermoid carcinoma). The cells HEp-2 were the most affected by the substances tested. (author)

Additional details

Identifiers

URL
http://www.scielo.br/pdf/jbchs/v16n6b/27350.pdf;

Publishing Information

Journal Title
Journal of the Brazilian Chemical Society
Journal Volume
16
Journal Issue
6B
Journal Page Range
p. 1454-1457
ISSN
0103-5053
CODEN
JOCSET

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
38030860
Subject category
S75: CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY;
Descriptors DEI
ANTIMITOTIC DRUGS; CARBON 13; CHEMICAL SHIFT; FLAVONOIDS; GAS CHROMATOGRAPHY; HYDROGEN 1; MASS SPECTRA; METHOXY RADICALS; NMR SPECTRA; PROPANOLS
Descriptors DEC
ALCOHOLS; ALKOXY RADICALS; CARBON ISOTOPES; CHROMATOGRAPHY; DRUGS; EVEN-ODD NUCLEI; HYDROGEN ISOTOPES; HYDROXY COMPOUNDS; ISOTOPES; LIGHT NUCLEI; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; RADICALS; SEPARATION PROCESSES; SPECTRA; STABLE ISOTOPES

Optional Information

Notes
12 refs., 1 fig., 2 tabs. Also available from http://www.scielo.br/pdf/jbchs/v16n6b/27350.pdf. Access on: 23 Mar 2007