Efficacy of radioiodine treatment in well-differentiated thyroid cancer in children

Well-differentiated thyroid cancer (WDTCA) in children is the third most common solid tumor malignancy and the most frequent endocrine malignancy in children. They are more aggressive at the time of diagnosis, with metastases, and have a higher risk for recurrence. The objective of this paper is to determine the efficacy of radioiodine treatment after 5-6 years from therapy. WDTCA in children is rare and the biological behavior differs from that of adults. Their presentation is quite aggressive and may be recurrent. Total or near-total thyroidectomy with ¹³¹I ablation reduces mortality and hence is efficacious