Prospects in biochemical methods application in testing local injuries and its modification
Creators
Description
A set of biochemical tests, characterizing the state of healthy organs of persons subjected to irradiation is created to develop models for preventing delayed radiation effects. Lipid peroxidation serves as a basic theory of radiation injury reaction. Functional and biochemical peculiarities of the organs are also considered. Diagnostic tests for salivary glands and liver are proposed. It is ascertained that determination methods of lipid peroxidation acid phosphatase activity can serve as indicators of liver radiation injury. Lipid peroxidation significantly increases in case of local irradiation of salivary glands and liver it is advisable to use synthetic antioxidants to decrease lipid peroxidation products in order to prevent biochemical changes in parenchymous organs and to promote organism detoxication
Additional details
Additional titles
- Original title (Russian)
- Перспективы в использовании биохимических методов при тестировании локальных лучевых поражений и их модификации
Publishing Information
- Imprint Title
- Actual problems of radiation safety in medicine. Results and prospects
- Journal Page Range
- p. 58-64.
- Report number
- INIS-SU--81/A
INIS
- Country of Publication
- USSR
- Country of Input or Organization
- USSR
- INIS RN
- 20033490
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOCHEMISTRY; BIOLOGICAL FUNCTIONS; BIOLOGICAL INDICATORS; BIOLOGICAL RADIATION EFFECTS; DOSE-RESPONSE RELATIONSHIPS; ENZYME ACTIVITY; HEPATECTOMY; LIPIDS; LIVER; LOCAL IRRADIATION; PHOSPHATASES; RADIOTHERAPY; RATS; SALIVARY GLANDS; SIDE EFFECTS; X RADIATION
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BODY; CHEMISTRY; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; GLANDS; HYDROLASES; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MEDICINE; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; SURGERY; THERAPY; VERTEBRATES
Optional Information
- Notes
- 8 refs.; 3 tabs. Imprint:Aktual'nye problemy radiatsionnoj bezopasnosti v meditsine. Itogi i perspektivy.;Sbornik nauchnykh trudov.