Published October 1982 | Version v1
Journal article Metadata-only

Synthesis and quality control of 125I- and 14C-labelled 5-iodo-2'-deoxycytidine triphosphate

Creators

  • 1. Kernforschungsanlage Juelich G.m.b.H. (Germany, F.R.). Inst. fuer Nuklearchemie

Description

A method is described for a no-carrier-added synthesis and purification of doubly-labelled [5-125I, U-14C]-iododeoxycytidine triphosphate. Iodination of 14C-dCTP was achieved with a radiochemical yield of 80%. Separation and purification of the reaction product were accomplished by reversed-phase high performance liquid chromatography (RP-HPLC). (author)

Additional details

Publishing Information

Journal Title
J. Labelled Compd. Radiopharm.
Journal Volume
19
Journal Issue
10
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
1151-1159

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
14741007
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CARBON 14; CARRIER-FREE ISOTOPES; CHEMICAL PREPARATION; CYTIDINE; DNA; DOUBLE LABELLING; IODINE 125; LABELLED COMPOUNDS; LIQUID COLUMN CHROMATOGRAPHY; MOLECULAR BIOLOGY; ORGANIC IODINE COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; PH VALUE; PHOSPHATES; QUALITY CONTROL; QUANTITY RATIO; SODIUM IODIDES; TIME DEPENDENCE
Descriptors DEC
ALKALI METAL COMPOUNDS; AZINES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CHROMATOGRAPHY; CONTROL; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; EVEN-EVEN NUCLEI; HALIDES; HALOGEN COMPOUNDS; HETEROCYCLIC COMPOUNDS; INORGANIC PHOSPHORS; INTERMEDIATE MASS NUCLEI; IODIDES; IODINE COMPOUNDS; IODINE ISOTOPES; ISOTOPES; LABELLING; LIGHT NUCLEI; NUCLEI; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; OXYGEN COMPOUNDS; PHOSPHORS; PHOSPHORUS COMPOUNDS; PYRIMIDINES; RADIOISOTOPES; RIBOSIDES; SEPARATION PROCESSES; SODIUM COMPOUNDS; SYNTHESIS; YEARS LIVING RADIOISOTOPES