Published April 20, 2000 | Version v1
Journal article Metadata-only

Early diagnosis of Alzheimer's disease. Clinical significance and future perspectives

Creators

  • 1. Muenchen Univ. (Germany). Psychiatrische Klinik und Poliklinik

Description

Early diagnosis of Alzheimer's disease describes the recognition and diagnosis in patients with very mild dementia. Internationally accepted diagnostic criteria support the diagnosis based on clinical evaluation. Recent advances in structural and functional neuroimaging as well as studies on specific proteins in the cerebro-spinal fluid that are related to distinct pathophysiological disease processes are most promising approaches to defining biological markers of Alzheimer's disease. (orig.)

Abstract (German)

Der Begriff 'Fruehdiagnose' der Alzheimer-Demenz (AD) bedeutet, das Demenzsyndrom moeglichst fruehzeitig, im beginnenden, klinisch fassbaren Stadium zu erkennen und diagnostisch exakt einzuordnen. Dazu empfiehlt es sich, nach international geltenden diagnostischen Leitlinien vorzugehen. Zentrale Grundlage der Diagnostik ist die klinisch-aerztliche Beurteilung. Viel versprechende Zukunftsperspektiven ergeben sich aktuell durch Fortschritte der strukturellen und funktionellen Bildgebung sowie der Liquorforschung. (orig.)

Additional details

Additional titles

Original title (German)
Alzheimer - schon Jahre vor den ersten Symptomen erkennbar? Wie Sie die beginnende Demenz anhand von klinischen Zeichen erfassen

Publishing Information

Journal Title
MMW. Muenchener Medizinische Wochenschrift
Journal Volume
142
Journal Issue
16
Journal Page Range
p. 26-30
ISSN
0341-3098
CODEN
MMMWD7

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
31033392
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ATROPHY; CEREBROSPINAL FLUID; COMPUTERIZED TOMOGRAPHY; DIAGNOSIS; ETIOLOGY; FLUORINE 18; FLUORODEOXYGLUCOSE; IMAGES; MAN; MENTAL DISORDERS; METABOLISM; NERVOUS SYSTEM DISEASES; NMR IMAGING; PATIENTS; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; SYMPTOMS; UPTAKE
Descriptors DEC
ANIMALS; ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY FLUIDS; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MAMMALS; MAN; MATERIALS; NANOSEC LIVING RADIOISOTOPES; NERVOUS SYSTEM DISEASES; NUCLEI; ODD-ODD NUCLEI; PATHOLOGICAL CHANGES; PRIMATES; RADIOACTIVE MATERIALS; RADIOISOTOPES; TOMOGRAPHY; VERTEBRATES