Published 1996
| Version v1
Journal article
Radioiodination of the protein complex of the VA-MENGOC-BC vaccine
Creators
- 1. Lastre, M. Instituto Finlay, La Habana (Cuba)
- 2. Centro de Isotopos (CENTIS), La Habana (Cuba)
- 3. Instituto Superior de Ciencia y Tecnologia Nuclear (ISCTN), La Habana (Cuba)
Description
In this work was made the labelling of the protein complex of the vaccine VAMENGOC-BC with iodine-125 in order to study its immunological responses. These proteins were in both forms: dissolved and conjugated with polisacarids of the C-group. The were used three methods of iodination: chloramine-T, iodogen and lactoperoxidase. Was found out that dissolved proteins can be iodinated using these three methods with 0.1 mCi of iodine-125, and the obtained specific activities were similar. Although the conjugated proteins can be iodinated only by two methods (chloramine-T and iodogen), the obtained specific activities were the same
Additional details
Additional titles
- Original title (Spanish)
- Yodacion del proteico de VA-MENGOC-BC
Publishing Information
- Journal Title
- Nucleus (Havana)
- Journal Issue
- no.21
- Journal Page Range
- p. 6-10.
- ISSN
- 0864-084X
- CODEN
- NCLSEY
INIS
- Country of Publication
- Cuba
- Country of Input or Organization
- Cuba
- INIS RN
- 28071210
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- IODINATION; IODINE 125; LABELLING; QUALITY CONTROL; RADIOCHROMATOGRAPHY
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; CHEMICAL REACTIONS; CHROMATOGRAPHY; CONTROL; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; HALOGENATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IODINE ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPES; SEPARATION PROCESSES