Implementation of a dedicated 1.5 T MR scanner for radiotherapy treatment planning featuring a novel high-channel coil setup for brain imaging in treatment position
- 1. Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (Germany)
Description
To share our experiences in implementing a dedicated magnetic resonance (MR) scanner for radiotherapy (RT) treatment planning using a novel coil setup for brain imaging in treatment position as well as to present developed core protocols with sequences specifically tuned for brain and prostate RT treatment planning. Our novel setup consists of two large 18-channel flexible coils and a specifically designed wooden mask holder mounted on a flat tabletop overlay, which allows patients to be measured in treatment position with mask immobilization. The signal-to-noise ratio (SNR) of this setup was compared to the vendor-provided flexible coil RT setup and the standard setup for diagnostic radiology. The occurrence of motion artifacts was quantified. To develop magnetic resonance imaging (MRI) protocols, we formulated site- and disease-specific clinical objectives. Our novel setup showed mean SNR of 163 ± 28 anteriorly, 104 ± 23 centrally, and 78 ± 14 posteriorly compared to 84 ± 8 and 102 ± 22 anteriorly, 68 ± 6 and 95 ± 20 centrally, and 56 ± 7 and 119 ± 23 posteriorly for the vendor-provided and diagnostic setup, respectively. All differences were significant (p > 0.05). Image quality of our novel setup was judged suitable for contouring by expert-based assessment. Motion artifacts were found in 8/60 patients in the diagnostic setup, whereas none were found for patients in the RT setup. Site-specific core protocols were designed to minimize distortions while optimizing tissue contrast and 3D resolution according to indication-specific objectives. We present a novel setup for high-quality imaging in treatment position that allows use of several immobilization systems enabling MR-only workflows, which could reduce unnecessary dose and registration inaccuracies.
Availability note (English)
Available from: http://dx.doi.org/10.1007/s00066-020-01703-yAdditional details
Identifiers
Publishing Information
- Journal Title
- Strahlentherapie und Onkologie
- Journal Volume
- 197
- Journal Issue
- 3
- Journal Page Range
- p. 246-256
- ISSN
- 0179-7158
- CODEN
- STONE4
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 52044378
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BRAIN; COMPARATIVE EVALUATIONS; DIAGNOSTIC USES; GLIOMAS; HEAD; IMAGE PROCESSING; IMAGE SCANNERS; MAGNETIC FIELDS; METASTASES; NMR IMAGING; PELVIS; POSITIONING; PROSTATE; RADIATION DOSES; RADIOTHERAPY; RELAXATION TIME; SIGNAL-TO-NOISE RATIO; SPATIAL RESOLUTION; WEIGHTING FUNCTIONS
- Descriptors DEC
- BODY; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DIMENSIONLESS NUMBERS; DISEASES; DOSES; EVALUATION; FUNCTIONS; GLANDS; MALE GENITALS; MEDICINE; NEOPLASMS; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; NUCLEAR MEDICINE; ORGANS; PROCESSING; RADIOLOGY; RESOLUTION; THERAPY; USES