Published January 1984
| Version v1
Report
Structural aspects of DNA in its replication and repair
Description
The research objective of this laboratory is to investigate the structure of DNA, the mechanism of DNA replication and its regulation, and the mechanism and role of repair of the altered DNA in the expression of heritable changes. This research has two broad aims, namely investigation of (a) the regulation of DNA replication in mammals, using parvovirus DNA as a model system and (b) the role of DNA repair in mutagenesis and carcinogenesis induced by simple alkylating mutagens
Additional details
Publishing Information
- Imprint Title
- Biology Division. Progress report, August 1, 1982-September 30, 1983
- Journal Page Range
- p. 7-11.
- Report number
- ORNL--6021
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 15067361
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- DNA; MOLECULAR STRUCTURE; NITROSO COMPOUNDS; NUCLEASES; NUCLEOTIDES; SULFUR 35; TRACER TECHNIQUES; TRANSFERASES; TRITIUM COMPOUNDS
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; ENZYMES; EVEN-ODD NUCLEI; HYDROGEN COMPOUNDS; ISOTOPE APPLICATIONS; ISOTOPES; LIGHT NUCLEI; NUCLEI; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PHOSPHOTRANSFERASES; RADIOISOTOPES; SULFUR ISOTOPES