Published 1979
| Version v1
Book
Effects of combined hyperthermia and ionizing radiation on melanoma cells
- 1. Essen Univ. (Gesamthochschule) (Germany, F.R.). Inst. fuer Medizinische Strahlenphysik und Strahlenbiologie
Description
DNA concentration, DNA synthesis rate, and relative DNA concentration were investigated after in-vitro hyperthermia and X-ray irradiation of human melanoma cells. Hyperthermia up to 420C and X-ray irradiation up to 400 Rdid not influence on cell proliferation; there were cell losses in the upper dose range, but proliferation of the surviving cells. Combined treatment had a synergitic effect. Cell losses were much higher after combined treatment than after only one type of treatment. However, in spite of considerable cell losses, there was no change in the DNA synthesis rate or the duration of the S-phase of the surviving cells. (orig.) 891 MG/orig. 892 RDG
Additional details
Additional titles
- Original title (German)
- Effekte nach der Kombination von Hyperthermie mit ionisierender Strahlung auf Melanomozellen
Publishing Information
- Publisher
- Urban und Schwarzenberg.
- Imprint Place
- Muenchen, Germany, F.R.
- ISBN
- 3-541-09021-9
- Imprint Title
- Combined radio- and chemotherapy
- Journal Issue
- no. 75
- Series
- Sonderbaende zur Strahlentherapie.
- Journal Page Range
- p. 75-81.
Conference
- Title
- Symposium of the Arbeitsgemeinschaften Strahlentherapie und Onkologie und Strahlenbiologie der Deutschen Roentgengesellschaft, Gesellschaft fuer Medizinische Radiologie und Nuklearmedizin e.V.
- Dates
- 20 - 21 Oct 1978.
- Place
- Bad Krozingen, Germany, F.R.
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 11521752
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BIOSYNTHESIS; CELL CULTURES; CELL CYCLE; CELL PROLIFERATION; DNA; DOSE-RESPONSE RELATIONSHIPS; HEAT TREATMENTS; IN VITRO; IRRADIATION; QUANTITY RATIO; SYNERGISM; THYMIDINE; TRACER TECHNIQUES; TRITIUM COMPOUNDS; TUMOR CELLS; UPTAKE; X RADIATION
- Descriptors DEC
- ANIMAL CELLS; AZINES; BIOLOGICAL EFFECTS; ELECTROMAGNETIC RADIATION; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; IONIZING RADIATIONS; ISOTOPE APPLICATIONS; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRIMIDINES; RADIATION EFFECTS; RADIATIONS; RIBOSIDES; SYNTHESIS
Optional Information
- Notes
- Imprint:Kombinierte Strahlen- und Chemotherapie.