Clinical effect of ¹³¹I combined with lithium carbonate in the treatment of graves' disease

Objective: To investigate the clinical curative effects of ¹³¹I combined with lithium carbonate therapy for Graves disease (GD). Methods: The clinical treatment materials of 5638 patients with GD patients were analyzed retrospectively. Results: The cure rate of patients with GD after one single cycle of ¹³¹I therapy combined with lithium carbonate was 76.5%, and the improve rate was 19.8%. The total effective rate was 96.3% among the 5638 GD patients. The total effective rate was 93.8% among 178 GD patients with hyperthyroid cardiopathy. Among all GD patients, the patients with hypothyroidism was observed 569 (10.1%) after the first ¹³¹I therapy. Conclusion: ¹³¹I combined with lithium carbonate therapy is an effective simple and safe method for the treatment of GD patients and GD patients with hyperthyroid cardiopathy. It may decrease the ¹³¹I treatment dose. (authors)