Published May 2005 | Version v1
Journal article Metadata-only

Dopamine mediated iron release from ferritin is enhanced at higher temperatures: Possible implications for fever-induced Parkinson's disease

Creators

  • 1. Department of Biophysics and Chemical Physics, Comenius University, Mlynska dolina F1, 842 48 Bratislava (Slovakia)

Description

A new molecular mechanism is proposed to explain the pathogenesis of fever-induced Parkinson's disease. This proposal is based on dopamine and 6-hydroxydopamine-mediated free iron release from ferritin magnetic nanoparticles, which is enhanced at higher temperatures, and which may lead to substantial peroxidation and injury of lipid biomembranes of the substantia nigra in the brain

Additional details

Identifiers

DOI
10.1016/j.jmmm.2005.02.029;
PII
S0304-8853(05)00179-4;

Publishing Information

Journal Title
Journal of Magnetism and Magnetic Materials
Journal Volume
293
Journal Issue
1
Journal Page Range
p. 341-344
ISSN
0304-8853
CODEN
JMMMDC

Conference

Title
5. International conference on scientific and clinical applications of magnetic carriers
Dates
20-22 May 2004
Place
Lyon (France)

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37029316
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BRAIN; DOPAMINE; FERRITIN; FEVER; IRON; LIPIDS; METABOLISM; NANOSTRUCTURES; NERVOUS SYSTEM DISEASES; PARTICLES; PATHOGENESIS
Descriptors DEC
AMINES; AROMATICS; AUTONOMIC NERVOUS SYSTEM AGENTS; BODY; CARDIOTONICS; CARDIOVASCULAR AGENTS; CENTRAL NERVOUS SYSTEM; COMPLEXES; DISEASES; DRUGS; ELEMENTS; HYDROXY COMPOUNDS; IRON COMPLEXES; METALLOPROTEINS; METALS; NERVOUS SYSTEM; NEUROREGULATORS; ORGANIC COMPOUNDS; ORGANS; PHENOLS; POLYPHENOLS; PROTEINS; SYMPATHOMIMETICS; SYMPTOMS; TRANSITION ELEMENT COMPLEXES; TRANSITION ELEMENTS

Optional Information

Copyright
Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.