Published January 2021 | Version v1
Journal article Metadata-only

Trends in NMR Structural Elucidation Of Polycyclic Cages, Namely: Adamantane, Pentacycloundecane and Trishomocubane

Creators

  • 1. Catalysis and Peptide Research Unit, School of Health Sciences, University of KwaZulu-Natal, Durban, 4001 (South Africa)
  • 2. Department of Biological, Physical and Health Sciences, College of Science, Health & Pharmacy, Roosevelt University, 425 South Wabash Avenue, Chicago, IL 60605 (United States)
  • 3. Department of Chemistry, University of Zululand, Private Bag X1001, KwaDlangezwa 3886 (South Africa)

Description

Advances in Nuclear Magnetic Resonance (NMR) spectroscopy is a cornerstone in structure elucidation of polycyclic 'cage' scaffolds. Due to the compactness of these compounds, much overlap, as well as unique through-space and bond NMR interactions are frequently observed. This review serves as a guide for the NMR elucidation of future derivatives by providing some of the typical and relevant aspects of the characteristic trends, substituent patterns and chemical shift behaviour for the identification of the polycyclic structures, namely adamantane, pentacycloundecane and trishomocubane derivatives. (author)

Availability note (English)

Available on-line: https://doi.org/10.17159/0379-4350/2021/v75a14

Additional details

Identifiers

DOI
10.17159/0379-4350/2021/v75a14;

Publishing Information

Journal Title
SA Journal of Chemistry (Online)
Journal Volume
75
Journal Page Range
p. 117-129
ISSN
1996-840X

INIS

Country of Publication
South Africa
Country of Input or Organization
South Africa
INIS RN
54107169
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S46: INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY;
Descriptors DEI
CHEMICAL SHIFT; CYCLOALKANES; NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY
Descriptors DEC
ALKANES; HYDROCARBONS; MAGNETIC RESONANCE; ORGANIC COMPOUNDS; RESONANCE

Optional Information

Notes
65 refs., 7 tabs., 4 figs.; © The Author(s) Published under a Creative Commons Attribution 4.0 International Licence (CC BY 4.0)