Published July 2004 | Version v1
Journal article

Spectroscopic studies of the interaction between DNA and fluorene dyes

  • 1. Institute of Physics, Kyiv (Ukraine)
  • 2. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv (Ukraine)
  • 3. University of Central Florida, Chemical Dept., Orlando (United States)

Description

Making use of electron spectroscopy and infrared vibrational spectroscopy methods, the interaction of the DNA taken from the normal and tumor tissues of rats of the Vistar line with two types of fluorene dyes. Experimental results evidence for that the dyes link more efficiently to the reference DNA than to the tumor one. The in vivo experiment shows that additional sites appear in the dyes for their linkage with DNA

Additional details

Publishing Information

Journal Title
Ukrayins'kij Fyizichnij Zhurnal (Kiev)
Journal Volume
49
Journal Issue
no.7
Journal Page Range
p. 636-647
ISSN
0372-400X