Published November 1981 | Version v1
Journal article

Tryptophan protection of phage from ultraviolet irradiation

  • 1. Clemson Univ., SC (USA)

Description

Bacteriophage SP02c12 and its isolated DNA were irradiated at 254 nm in tryptophan solutions. At a concentration of 10 mM, the amino acid exerted a protective effect on intact virus. The magnitude of this effect depended upon the length of time elapsed between mixing and irradiation. No protection was observed for solutions irradiated immediately after mixing. Tryptophan did not have a significant effect on UV sensitivity of the isolated viral DNA. No covalent crosslinking of tryptophan to DNA was observed. (author)

Additional details

Publishing Information

Journal Title
Photochem. Photobiol.
Journal Volume
34
Journal Issue
5
Series
Photochem. Photobiol.
Journal Page Range
583-587
ISSN
0031-8655