Published May 15, 1988
| Version v1
Journal article
Effects of diphosphonate and x-rays on bone lesions induced in rats by prostate cancer cells
Description
Prostate adenocarcinoma-III (PA-III) cells deposited over the scapula of Lobund-Wistar (L-W) rats induced osteolytic and osteoplastic changes in that bone. The osteolytic process was prevented and interrupted by administrations of dichloromethylene diphosphonate (Cl2MDP); but the osteoplastic process, once initiated, continued. The latter process was interrupted by ionizing radiation. Treatments of PA-III-affected bones with Cl2MDP and x-rays immobilized both osteolytic and osteoplastic processes
Additional details
Publishing Information
- Journal Title
- Cancer (Philadelphia)
- Journal Volume
- 61
- Journal Issue
- 10
- Series
- Cancer (Philadelphia).
- Journal Page Range
- 2027-2032
- ISSN
- 0008-543X
- CODEN
- CANCA
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 19088038
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CARCINOMAS; PHOSPHONATES; PROSTATE; RATS; SKELETON; SYNERGISM; TRANSPLANTS; TUMOR CELLS; X RADIATION
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BODY; DISEASES; ELECTROMAGNETIC RADIATION; GLANDS; IONIZING RADIATIONS; MALE GENITALS; MAMMALS; NEOPLASMS; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES