Published 1987 | Version v1
Journal article Metadata-only

The quantitative analysis of arteritis induced by X-irradiation in rats

Creators

  • 1. Hiroshima Univ. (Japan). Research Inst. for Nuclear Medicine and Biology

Description

The arteritis induced by whole body or gastric region of X-irradiation was examined in both sexes 5- or 8-week-old rats. Arteritis showed fibrinoid necrosis with massive inflammatory cell infiltration, and elastic fibers and smooth muscle cells were partially or completely denatured. The outer layer of arteries replaced by the granulation and arterial walls were markedly thickened over 10 Gy fractions of X-irradiation but not under 5 Gy. Thickness of arterial walls was note on the dose response by using color image analyzer for quantitative analysis. Arteritis induced by X-irradiation in rats was promoted by NaCl, but alcohol did not influence for the development of arteritis. (author)

Additional details

Publishing Information

Journal Title
Hiroshima Daigaku Genbaku Hoshano Igaku Kenkyusho Nenpo
Journal Issue
no.28
Series
Hiroshima Daigaku Genbaku Hoshano Igaku Kenkyusho Nenpo.
ISSN
0073-232X
CODEN
HDGHA

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
19027094
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ARTERIES; DOSE-RESPONSE RELATIONSHIPS; HYPERTROPHY; INFLAMMATION; LOCAL IRRADIATION; NECROSIS; RADIATION INJURIES; RATS; STOMACH; WHOLE-BODY IRRADIATION; X RADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; DIGESTIVE SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; GASTROINTESTINAL TRACT; INJURIES; IONIZING RADIATIONS; IRRADIATION; MAMMALS; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES