Published June 1980 | Version v1
Journal article Metadata-only

The development, production and quality control of radioimmuno assaying kits

Creators

  • 1. Atomic Energy Board, Pelindaba, Pretoria (South Africa). Chemistry Div.

Description

Radioimmuno assaying is an extremely sensitive analytical technique used in diagnostic medicine for the determination of minute quantities of hormones, drugs and other substances in serum. Low concentrations in the order of 10-12g can be determined. The development and production of commercial kits comprise the preparation of radioactive labelled antigens; non radioactive labelled standard antigens; antigen specific antibodies; fast and reliable separation techniques. To ensure the supply of high quality material it is necessary to follow various strict quality control measures

Abstract (Afrikaans)

Die radio-immuno-essaieringstegniek is 'n hoogs sensitiewe analitiese metode wat in die diagnostiese geneeskunde gebruik word vir die bepaling van hormone, geneesmiddels en ander stowwe wat in serum voorkom. Lae konsentrasies van 10-12g/cm3 is bepaalbaar. Die ontwikkeling en produksie van kommersiele stelle vir radio-immuno-essaiering behels die bereiding van radioaktief gemerkte antigene; nie-radio-aktief gemerkte standaardantigene; antigeenspesifieke teenliggame en geskikte vinnige skeitegnieke. Om te verseker dat produkte van hoogstaande gehalte gelewer word, is dit noodsaaklik dat verskeie gehaltebeheermaatreels streng nagekom word

Additional details

Additional titles

Original title (Afrikaans)
Die ontwikkeling, produksie en gehaltebeheer van radio-immuno-essaieringstelle

Publishing Information

Journal Title
Tegnikon
Journal Volume
28
Journal Issue
2
Series
Tegnikon.
Journal Page Range
6-9
ISSN
0040-215X

INIS

Country of Publication
South Africa
Country of Input or Organization
South Africa
INIS RN
11554519
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S60: APPLIED LIFE SCIENCES;
Descriptors DEI
ANTIGEN-ANTIBODY REACTIONS; DIAGNOSTIC TECHNIQUES; LABELLED COMPOUNDS; PRODUCTION; QUALITY CONTROL; RADIOIMMUNOASSAY
Descriptors DEC
CONTROL; ISOTOPE APPLICATIONS; TRACER TECHNIQUES