Transthyretin Amyloidosis (ATTR): The role of multimodality in the definitive diagnosis

Transthyretin amyloidosis (ATTR) is a rare cause of restrictive cardiomyopathy and/or peripheral polyneuropathy, of a progressive, irreversible and fatal nature, underdiagnosed and with its definitive diagnosis performed late ¹. Early diagnosis, characterization of the type of amyloidosis and subsequent establishment of specific therapy are fundamental for a better prognosis of this disease ¹. We present a case of ATTR where clinical suspicion associated with multimodality diagnosis - nuclear medicine - was able to safely deliver diagnosis, without the need for biopsy ². (author)