Study on the relationship between levels of serum thrombopoietin (TPO) and hepatic fibrosis markers in patients with chronic liver diseases
Creators
- 1. Department of Laboratory Medicine, Taizhou People's Hospital, Taizhou (China)
Description
Objective: To study the relationship between serum thrombopoietin (TPO) and hepatic fibrosis markers levels in patients with chronic liver disease. Methods: Serum thrombopoietin levels were detected and hepatic fibrosis markers with ELISA (HA, LN, PCIII, IVC) in 114 patients with various types of chronic hepatitis and 30 controls. Results: The serum TPO levels in patients with different types of chronic hepatitis inducing cirrhosis were not significantly different from those in controls (P>0.05). Serum TPO levels were correlated with the levels of IVC in the 18 patients with cirrhosis (r=0.517, P<0.05), but not with only hepatic fibrosis marker in any other group of patients. Conclusion: Serum TPO levels was not correlated with the severity of chronic hepatitis but was somewhat correlated with the degree of fibrosis in patients with cirrhosis. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 21
- Journal Issue
- 1
- Journal Page Range
- p. 29-31
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 41053264
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOLOGICAL MARKERS; BLOOD SERUM; COLLAGEN; CORRELATIONS; ENZYME IMMUNOASSAY; FIBROSIS; HEPATITIS; HYALURONIC ACID; LIVER; RADIOIMMUNOASSAY; THROMBOPOIESIS
- Descriptors DEC
- AMINES; BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD FORMATION; BLOOD PLASMA; BODY; BODY FLUIDS; CARBOHYDRATES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; GLANDS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MUCOPOLYSACCHARIDES; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; POLYSACCHARIDES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SACCHARIDES; SCLEROPROTEINS; TRACER TECHNIQUES
Optional Information
- Notes
- 2 tabs., 11 refs.