Published January 2010 | Version v1
Journal article Metadata-only

Biodistribution and pharmacokinetics of 99mTc-ciprofloxalina obtained from a modified formulation

Creators

  • 1. Centro de Investigaciones Clinicas, La Habana (Cuba)

Description

The aim of the present investigation was to evaluate the biokinetics performance of 99mTc-ciprofloxacin obtained from a new formulation. Both in vitro assays and experimental infection models demonstrated its affinity for viable bacteria.Half life in blood was 5.89 ± 0.85 hours. The biodistribution showed high accumulation on infected muscles and low on healthy tissues

Availability note (English)

Available as electronic journal from the website: http://www.alasbimnjournal.cl/

Additional details

Additional titles

Original title (Spanish)
Biodistribucion y farmacocinetica de

Identifiers

URL
http://www.alasbimnjournal.cl/;

Publishing Information

Journal Title
Alasbimn Journal
Journal Volume
12
Journal Issue
47
Journal Page Range
[6 p.]
ISSN
0717-4055

INIS

Country of Publication
Chile
Country of Input or Organization
Chile
INIS RN
41113804
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BACTERIA; BONE TISSUES; NUCLEAR MEDICINE; PHARMACOLOGY; SCINTISCANNING; TECHNETIUM 99
Descriptors DEC
ANIMAL TISSUES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CONNECTIVE TISSUE; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MICROORGANISMS; NUCLEI; ODD-EVEN NUCLEI; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
9 Refs., 4 Graph., 2 Tabs., 3 Fig