Published December 2006 | Version v1
Journal article

Effect of erythropoietin on photodynamic therapy of ovarian adenocarcinomas A2780 and SKOV-3

  • 1. Institute of Biology and Ecology, Faculty of Sciences, P. J. Safarik University, 04001 Kosice (Slovakia)

Description

Erythropoietin is a cytokine with a pleiotropic effect. It is the principal haematopoietic growth factor, has a proangiogenic and protective effect in diverse nonhaematopoietic organs. In our experiment cell proliferation and/or survival assay was used to demonstrate Epo's cytoprotective effect against the photodynamic therapy of hypericin. Epo protected SKOV-3 cells against the cytotoxic effect of hypericin. These results advocate a restricted use of Epo on cancer patients with EpoR positive tumors. (authors)

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Introduction

Additional details

Publishing Information

Journal Title
Folia Veterinaria
Journal Volume
50
Journal Issue
3,Suppl.2006
Series
Toropila, M. (ed.), University of Veterinary Medicine in Kosice, Slovakia; Fourteen papers were published in this numer. Forty-seven papers papers were published in Proceedings of the 3"r"d Radiobiological Conference 2006 (see also INIS RN 37:103156)
Journal Page Range
p. 28-29
ISSN
0015-5748

Conference

Title
The Third Radiobiological Conference 2006. International Conference held on occasion of 20 years anniversary of the tragic accident in Chernobyl (Ukraine)
Original Conference Title
3. Radiobiologicka konferencia 2006. Medzinarodna konferencia venovana 20. vyrociu jadrovej havarie v Cernobyle
Dates
25 May 2006
Place
Kosice (Slovakia)

Optional Information

Notes
6 refs., 2 figs.; See also INIS RN 37:103195; E-mail: solarp@upjs.sk