A clinical study of infantile bronchial asthma by radioallergosorbent test (RAST), 2

RAST for house dust, RAST for egg white, and RAST for milk were performed in the serum of 91 cases of infantile bronchial asthma, 25 cases, and 29 cases of infantile allergic diseases picked up at random, respectively. 1) When using reference disc of three different lots, uptake counts of reference sera A, B, C and D showed the following scatters for added counts; A: 28.1-21.4%, B: 12.1-9.7%, C: 4.5-3.0%, and D: 2.8-2.2%. 2) When over 5% of added counts was defined as positive, a consistency of RAST for house dust with P-K test or induction test was 37/42 (88.1%) and 12/14 (85.7%), respectively. 3) When over 3% of added counts was defined as positive, a consistency of RAST for house dust with P-K test or induction test was 39/42 (92.8%) and 14/14 (100%), respectively. This consistency was better than that in positive case with over 5% of added counts. 4) When over 3% of RAST titer was defined as positive, the consistency with the diameter of flush area by intradermal test and in stretching of swelling by scratch test was 59/69 (85.5%) and 23/29 (79.3%), respectively. 5) When over 3% of RAST titer for house dust was defined as positive, cases which showed positive at lower concentration than 1:10,000 of intradermal test threshold was 56/61 (91.8%). 6) The positive in RAST for house dust was not recognized in infants of under 2 years old, but it was recognized in 50% of infants of 2 years old, and it was also recognized with high frequency in infants of over 3 years old. 7) The positive in RAST for egg white and milk was recognized in infants of under 2 years old, and not in infants of over 4 years old. (Tsunoda, M.)