Published July 1975 | Version v1
Journal article

Control of thymidine kinase synthesis in IHD vaccinia virus-infected thymidine kinase-deficient LM cells

  • 1. Weizmann Inst. of Science, Rehovoth, Israel

Description

The synthesis of vaccinia virus-induced thymidine kinase is normally arrested several hours after infection. In thymidine kinase-deficient LM cells infected with IHD strain of vaccinia virus, arrest occurs whether or not viral DNA synthesis is inhibited. With virus inactivated by uv irradiation, enzyme synthesis takes place, but arrest is abolished. It is suggested that an early viral genetic function is responsible for the cessation of thymidine kinase synthesis

Additional details

Additional titles

Augmented title (English)
UV radiation

Publishing Information

Journal Title
Journal of Virology
Journal Volume
16
Journal Issue
1
Series
J. Virol.
Journal Page Range
210-213
ISSN
0022-538X

Optional Information

Notes
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