Published March 1990 | Version v1
Journal article Metadata-only

Prevention and treatment of experimental radiation damages to skin with nuclyderm-gel

Creators

  • 1. Meditsinska Akademiya, Sofia (Bulgaria). Nauchen Inst. po Rentgenologiya i Radiobiologiya

Description

Radiopreventive and radiotherapeutic efficacy of nuclyderm-gel was studied on tails of mice exposed to fractionated γ-radiation of 90 Gy (15+30+45 Gy) and 75 Gy (45+30 Gy). Daily seven-day treatment with nuclyderm-gel prior to irradiation with increasing doses (15+30+45 Gy) and the subsequent continuous therapy were shown to delay and reduce skin reactions. Nuclyderm-gel was particularly effective when used therapeutically. The treatment of exposed areas, with the three-fold dose fractionation, was the optimum therapy scheme

Additional details

Additional titles

Original title (Russian)
Профилактика и лечение экспериментальных лучевых повреждений кожи с помощью препарата нуклидерм-гель

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
30
Journal Issue
2
Series
Radiobiologiya.
Journal Page Range
272-275
ISSN
0033-8192
CODEN
RADOA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
22043198
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
COBALT 60; FRACTIONATED IRRADIATION; GELS; INTEGRAL DOSES; LOCAL IRRADIATION; MICE; NUCLEOTIDES; RADIODERMATITIS; RADIOPROTECTIVE SUBSTANCES; SKIN
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; COBALT ISOTOPES; COLLOIDS; DERMATITIS; DISEASES; DISPERSIONS; DRUGS; INJURIES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LOCAL RADIATION EFFECTS; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIATION DOSES; RADIATION EFFECTS; RADIATION INJURIES; RADIOISOTOPES; RESPONSE MODIFYING FACTORS; RODENTS; SKIN DISEASES; VERTEBRATES; YEARS LIVING RADIOISOTOPES