Published March 1994
| Version v1
Journal article
Mechanism of chromosome loss during irradiation of mature Drosophila sperm
- 1. Institute of Cytology and Genetics, Novosibirsk (Russian Federation)
Description
The frequency of radiation-induced chromosome loss depends not only on the total content of DNA in the chromosome, but also on the size of the juxtacentromeric heterochromatin block. This relationship is selective and results from a dominant lethal effect due to failure to repair breaks in euchromatin. Simultaneous loss of two chromosomes in a single nucleus is not an independent consequence of the interaction of heterochromatin breaks which are responsible for this loss. It is concluded that chromosome loss occurs during exchange events accompanied by centromere deletions
Additional details
Publishing Information
- Journal Title
- Soviet Genetics
- Journal Volume
- 29
- Journal Issue
- 9
- Journal Page Range
- p. 1090-1095.
- ISSN
- 0038-5409
- CODEN
- SOGEBZ
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 26005494
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Translation
- Descriptors DEI
- CHROMOSOME BREAKAGE; CHROMOSOMES; DNA REPAIR; GAMMA RADIATION; GENETIC RADIATION EFFECTS; LOSSES; SPERMATOZOA; STRAND BREAKS
- Descriptors DEC
- BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; CHROMOSOMAL ABERRATIONS; ELECTROMAGNETIC RADIATION; GAMETES; GENETIC EFFECTS; GERM CELLS; IONIZING RADIATIONS; MUTATIONS; RADIATION EFFECTS; RADIATIONS
Optional Information
- Notes
- Translated from Genetika; 29: No. 9, 1468-1475(Aug 1993). Cover-to-cover-translation of Genetika.