Study of moderator thickness for an accelerator-based neutron irradiation facility for boron neutron capture therapy using the 7Li(p, n) reaction near threshold
Creators
- 1. Australian Radiation Protection and Nuclear Safety Agency, PO Box 655, Miranda, 1490, NSW (Australia)
- 2. St. George Cancer Care Centre, Gray Street, Kogarah, 2217, NSW (Australia)
Description
Accelerator neutron sources for epithermal neutron capture therapy utilizing the 7Li(p, n) nuclear reaction will require a moderator even in the threshold range of 1.89 to 1.95 MeV. The corresponding neutron energies allow for a thinner reflector and moderator, with less reduction of the epithermal flux. To estimate the useful neutron flux within the epithermal range (4 eV-40 keV), the optimal thickness of a heavy water moderator was determined using the two-dimensional neutron transport SN code DORT. Optimized results are compared with the epithermal fluxes reported for the higher proton energy range, and are found to be inferior. Thus, this study supports the 2.5-3.0 MeV proton energy range for accelerator boron neutron capture therapy. (author)
Additional details
Publishing Information
- Journal Title
- Physics in Medicine and Biology (Online)
- Journal Volume
- 45
- Journal Issue
- 1
- Journal Page Range
- p. 59-67
- ISSN
- 1361-6560
INIS
- Country of Publication
- International Atomic Energy Agency (IAEA)
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 31022207
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S73: NUCLEAR PHYSICS AND RADIATION PHYSICS;
- Descriptors DEI
- EPITHERMAL NEUTRONS; LITHIUM 7 REACTIONS; NEUTRON CAPTURE THERAPY; OPTIMIZATION; PROTON BEAMS; THRESHOLD DOSE; THRESHOLD ENERGY
- Descriptors DEC
- BARYONS; BEAMS; ELEMENTARY PARTICLES; ENERGY; FERMIONS; HADRONS; HEAVY ION REACTIONS; MEDICINE; NEUTRON THERAPY; NEUTRONS; NUCLEAR REACTIONS; NUCLEON BEAMS; NUCLEONS; PARTICLE BEAMS; RADIATION DOSES; RADIOTHERAPY; THERAPY