Published January 1977 | Version v1
Journal article

Gluconeogenesis in rat placenta during foetal development

  • 1. Bhabha Atomic Research Centre, Bombay (India). Biochemistry and Food Technology Div.

Description

Variations in glycogen levels in rat placenta have been correlated with gluconeogenesis in this tissue. Placental homogenate could synthesize substantial amounts of glucose from L-alanine-U-14C in early pregnancy. This has been substantiated by the observed enhancement in the activities of glucose 6-phosphatase, fructose 1, 6-diphosphatase and phosphoenolpyruvate carboxykinase. Gluconeogenic activity in placenta could proceed till the foetal liver was able to take over this function. The increase or decrease in placental glycogen is concomitant with glycogen synthetase, but not phosphorylase, activity. The reversible catalytic properties of placental aldolase also show subtle functional changes during and late phases of gestation. (author)

Additional details

Publishing Information

Journal Title
Indian J. Exp. Biol.
Journal Volume
15
Journal Issue
1
Journal Series
Indian J. Exp. Biol.
Journal Page Range
27-29

Optional Information

Notes
27 refs.