Published June 1985
| Version v1
Journal article
A new procedure for the preparation of 11C-labelled methyl iodide
- 1. Deutsches Krebsforschungszentrum, Heidelberg (Germany, F.R.). Inst. fuer Nuklearmedizin
Description
The use of diphosphorous tetraiodide for the preparation of [11C]methyl iodide from [11C]methanol has been investigated. This method offers several practical advantages over the established procedure using hydrogen iodide. [11C]Methyl iodide, produced by this new route, has been obtained in a radiochemical yield of 80-90% with a radiochemical purity of 99.5%. The specific activity of the product has been determined and was 3.4 ci/μmol. The reagent P2I4 is reusable for several preparations. (author)
Additional details
Publishing Information
- Journal Title
- Int. J. Appl. Radiat. Isot.
- Journal Volume
- 36
- Journal Issue
- 6
- Series
- Int. J. Appl. Radiat. Isot.
- Journal Page Range
- 435-438
- ISSN
- 0020-708X
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 16076947
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- CARBON DIOXIDE; CARBON 11; CHEMICAL PREPARATION; CHEMICAL REACTION YIELD; GAS CHROMATOGRAPHY; LABELLED COMPOUNDS; METHANOL; METHYL IODIDE; PHOSPHORUS IODIDES
- Descriptors DEC
- ALCOHOLS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON COMPOUNDS; CARBON ISOTOPES; CARBON OXIDES; CHALCOGENIDES; CHROMATOGRAPHY; EVEN-ODD NUCLEI; HALIDES; HALOGEN COMPOUNDS; HYDROXY COMPOUNDS; IODIDES; IODINE COMPOUNDS; ISOTOPES; LIGHT NUCLEI; MINUTES LIVING RADIOISOTOPES; NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; PHOSPHORUS COMPOUNDS; RADIOISOTOPES; SEPARATION PROCESSES; SYNTHESIS