Published 1993 | Version v1
Journal article Metadata-only

The tritium-labelled preparations of choline series

Creators

Description

Methods of preparation of tritium-labelled choline-chloride, acetylcholinechloride, phosphorylcholinechloride and chlorinecholinechloride were developed. Tritium label was introduced into [methyl-3H] cholinechloride via quaternization of dimethylethanolamine by highly active iodide of [3H] methyl. By means of acetylation, phosphorylation and chlorination of [methyl-3H] cholinechloride, phosphoryl [methyl-3H] cholinechloride and chlorine[methyl-3H] cholinechloride were synthesized respectively. Molar activity of the labelled preparations synthesized is 1480-2960 TBq/mol (40-80 kCi/mol)

Additional details

Additional titles

Original title (Russian)
Меченные тритием препараты холинового ядра

Publishing Information

Journal Title
Radiokhimiya
Journal Volume
35
Journal Issue
1
Journal Page Range
p. 100-106.
ISSN
0033-8311
CODEN
RADKAU

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
25000239
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
ACETYLCHOLINE; CHEMICAL PREPARATION; CHEMICAL REACTION KINETICS; CHLORIDES; CHOLINE; LABELLED COMPOUNDS; RADIOACTIVITY; TRITIUM COMPOUNDS
Descriptors DEC
ALCOHOLS; AMINES; AUTONOMIC NERVOUS SYSTEM AGENTS; CHLORINE COMPOUNDS; DRUGS; ESTERS; HALIDES; HALOGEN COMPOUNDS; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; KINETICS; LIPOTROPIC FACTORS; NEUROREGULATORS; ORGANIC COMPOUNDS; PARASYMPATHOMIMETICS; QUATERNARY COMPOUNDS; REACTION KINETICS; SYNTHESIS