Published March 2019 | Version v1
Journal article

Phase 2 Study of Radiation Therapy Plus Low-Dose Temozolomide Followed by Temozolomide and Irinotecan for Glioblastoma: NRG Oncology RTOG Trial 0420

  • 1. University of Pittsburgh Medical Center, University of Pittsburgh Physicians, Department of Neurology, Department of Medicine, Pittsburgh (United States)
  • 2. Merck & Co, Kenilworth, New Jersey (United States)
  • 3. University of Wisconsin, Madison (United States)
  • 4. Washington University School of Medicine, St Louis (United States)
  • 5. Emory University, Atlanta (Georgia)

Description

To evaluate the toxicity and efficacy of adjuvant temozolomide (TMZ) and irinotecan (CPT-11) for 12 months after concurrent chemoradiation in patients with newly diagnosed glioblastoma (GBM).

Additional details

Identifiers

DOI
10.1016/j.ijrobp.2018.11.008;
PII
S0360301618339555;

Publishing Information

Journal Title
International Journal of Radiation Oncology, Biology and Physics
Journal Volume
103
Journal Issue
4
Journal Page Range
p. 878-886
ISSN
0360-3016
CODEN
IOBPD3

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55057244
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
DIAGNOSIS; GLIOMAS; PATIENTS; RADIOTHERAPY; THERAPEUTIC DOSES; TOXICITY
Descriptors DEC
DISEASES; DOSES; MEDICINE; NEOPLASMS; NERVOUS SYSTEM DISEASES; NUCLEAR MEDICINE; RADIOLOGY; THERAPY

Optional Information

Copyright
Copyright (c) 2018 Published by Elsevier Inc.